Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045500 | 0.92 | OPRM1 (0.69) | OPRM1OPRD1OPRK1CACNA1CSIGMAR1 | |
| Oxalic Acid SCHEMBL6045761 | 0.90 | OPRM1 (0.67) | OPRM1OPRD1OPRK1CACNA1CSIGMAR1 | |
| SCHEMBL11566707 | 0.90 | OPRM1 (0.85) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11569120 | 0.88 | OPRM1 (0.80) | OPRM1OPRD1OPRK1CACNA1C | |
| Fumaric Acid SCHEMBL6045658 | 0.88 | OPRM1 (0.63) | OPRM1OPRD1OPRK1CACNA1C | |
| Maleic Acid SCHEMBL6045651 | 0.88 | OPRM1 (0.63) | OPRM1OPRD1OPRK1CACNA1C | |
| Oxalic Acid SCHEMBL8772964 | 0.86 | OPRM1 (0.77) | OPRM1OPRD1OPRK1CACNA1C | |
| Oxalic Acid SCHEMBL6045521 | 0.85 | OPRM1 (0.61) | OPRM1OPRD1OPRK1CACNA1CSIGMAR1 | |
| SCHEMBL6045452 | 0.85 | OPRM1 (0.62) | OPRM1OPRD1OPRK1CACNA1CSIGMAR1 | |
| Oxalic Acid SCHEMBL6045491 | 0.85 | OPRM1 (0.60) | OPRM1OPRD1OPRK1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |