SCHEMBL11564217

SCHEMBL11564217

COC(COc1cc(C)cc(O)c1)OC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
CYP3A4 P08684 2/20 0.35
ALPL P05186 1/20 0.33
ALPI P09923 1/20 0.33
ALPG P10696 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HCAR1 Q9BXC0 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17204240 0.81 ALDH1A1 (0.44) PTPN1ALDH1A1KMT2APOLBTSHR
SCHEMBL11564858 0.81 CHRNB4 (0.43) ALDH1A1KMT2ATSHRCYP3A4CYP2C9
SCHEMBL17204118 0.80 ALDH1A1 (0.43) PTPN1ALDH1A1KMT2APOLBTSHR
SCHEMBL973210 0.79 ALDH1A1 (0.41) PTPN1ALDH1A1KMT2APOLBTSHR
SCHEMBL19929839 0.76 SLC7A5 (0.46) ALDH1A1POLBTSHR
SCHEMBL9774077 0.75 ALDH1A1 (0.50) PTPN1ALDH1A1KMT2APOLBMEN1
SCHEMBL11564256 0.73 RAB9A (0.42) KMT2ACYP2C19MEN1ADRB2
SCHEMBL11564369 0.73 ALDH1A1 (0.35) ALDH1A1KMT2ATSHRMEN1RECQL
SCHEMBL11563229 0.73 PTGS1 (0.50) TSHRCYP2C9CYP2C19ADRB2ADRB1
SCHEMBL25437942 0.73 ACHE (0.53) KMT2AMEN1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163112-A INSECTICIDES VELSICOL CHEMICAL CORPORATION (US) 1979-07-31 US disclosed