Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 6/20 | 0.42 |
| ▸ | NOS1 | P29475 | 6/20 | 0.42 |
| ▸ | NOS2 | P35228 | 6/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077303 | 0.89 | ALDH1A1 (0.48) | TAAR1HRH3HTR7NOS3NOS1 | |
| SCHEMBL28071130 | 0.84 | TAAR1 (0.59) | TAAR1HRH3HTR7CHRNA7 | |
| SCHEMBL10169147 | 0.80 | NOS1 (0.44) | TAAR1HRH3NOS3NOS1NOS2 | |
| SCHEMBL5163115 | 0.78 | HRH3 (0.44) | TAAR1HRH3HTR7NOS3NOS1 | |
| SCHEMBL3690305 | 0.78 | ALDH1A1 (0.44) | TAAR1HRH3 | |
| SCHEMBL3055268 | 0.78 | TAAR1 (0.63) | TAAR1HRH3HTR7CHRNA7 | |
| SCHEMBL427399 | 0.78 | NOS1 (0.51) | HRH3NOS3NOS1NOS2 | |
| SCHEMBL25975331 | 0.76 | CHRNA7 (0.52) | TAAR1HRH3HTR7NOS3NOS1 | |
| SCHEMBL3046909 | 0.75 | HRH3 (0.70) | TAAR1HRH3CHRNA7 | |
| SCHEMBL15872023 | 0.74 | ALDH1A1 (0.46) | TAAR1HRH3NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000490-A1 | Substituted naphthyridinones, processes for their preparations and therapeutical applications | MERCK & CO. INC. (US) | 1979-02-07 | — | — | EP | disclosed |