Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | TKT | P29401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174182 | 0.79 | CHRNB2 (0.48) | HRH3TKTCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL26031611 | 0.78 | CHRNA7 (0.50) | CHRNA7NOS1NOS3TAAR1HRH3 | |
| SCHEMBL2260183 | 0.78 | TAAR1 (0.55) | CHRNA7NOS1NOS3TAAR1HRH3 | |
| SCHEMBL4289948 | 0.77 | TKT (0.44) | NOS1NOS2TKTCYP3A4CYP11B1 | |
| SCHEMBL4410512 | 0.77 | NOS1 (0.42) | NOS1NOS3NOS2TKTCYP3A4 | |
| SCHEMBL11564261 | 0.76 | TAAR1 (0.50) | CHRNA7NOS1NOS3TAAR1HRH3 | |
| SCHEMBL6630716 | 0.75 | TKT (0.54) | NOS1NOS2TKTCYP3A4CYP11B1 | |
| SCHEMBL27955068 | 0.75 | NOS1 (0.41) | NOS1NOS2TKTCYP3A4CYP11B1 | |
| SCHEMBL9921224 | 0.73 | TDP1 (0.44) | NOS1NOS3HRH3NOS2TKT | |
| Hydrochloric Acid SCHEMBL27866323 | 0.73 | CYP11B1 (0.40) | NOS1NOS2TKTCYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |