Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1218609 | 0.76 | NOTUM (0.59) | NOTUMMAP4K4VCPSIRT7KDM4E | |
| SCHEMBL1219485 | 0.73 | NOTUM (0.56) | NOTUMMAP4K4VCPSIRT7KDM4E | |
| SCHEMBL7902821 | 0.73 | CA12 (0.57) | NOTUMMAP4K4VCPSIRT7KDM4E | |
| SCHEMBL2926217 | 0.73 | PLAU (0.43) | NOTUMALOX15GAATSHRCASP1 | |
| SCHEMBL24636886 | 0.72 | VCP (0.53) | NOTUMVCPSIRT7FLT1FLT4 | |
| SCHEMBL29621095 | 0.72 | VCP (0.53) | NOTUMVCPSIRT7FLT1FLT4 | |
| SCHEMBL29620924 | 0.71 | VCP (0.62) | VCPSIRT7FLT1FLT4KDR | |
| SCHEMBL22925926 | 0.71 | VCP (0.62) | VCPSIRT7FLT1FLT4KDR | |
| SCHEMBL1220436 | 0.70 | NOTUM (0.72) | NOTUMMAP4K4VCPSIRT7KDM4E | |
| SCHEMBL10555140 | 0.69 | ALDH1A1 (0.44) | NOTUMKDM4EALOX15NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151168-A | 5-Phenyl-2-oxazole carboximidamides as antidepressants | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-04-24 | — | — | US | disclosed |