Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564534 | 0.82 | APEX1 (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL11564288 | 0.80 | S1PR1 (0.41) | S1PR1KDRPDK1NOTUMLMNA | |
| SCHEMBL11268824 | 0.80 | KDR (0.44) | S1PR1KDRPDK1NOTUMLMNA | |
| Hydrochloric Acid SCHEMBL11727190 | 0.79 | KDR (0.43) | S1PR1KDRPDK1NOTUMLMNA | |
| SCHEMBL11514591 | 0.77 | MLYCD (0.51) | S1PR1KDRPDK1NOTUMKDM4E | |
| SCHEMBL28901346 | 0.75 | KDR (0.47) | S1PR1KDRPDK1NOTUMLMNA | |
| SCHEMBL11566296 | 0.74 | NPSR1 (0.48) | SMN1; SMN2NPSR1KDM4EHDAC8 | |
| SCHEMBL11566897 | 0.72 | HDAC3 (0.39) | — | |
| SCHEMBL8410111 | 0.71 | S1PR1 (0.45) | S1PR1KDRPDK1NOTUMLMNA | |
| SCHEMBL4246399 | 0.70 | HTR3E (0.49) | S1PR1KDRPDK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | claimed |
| US-4137068-A | Novel ureas | ROUSSEL UCLAF (FR) | 1979-01-30 | — | — | US | disclosed |