Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.58 |
| ▸ | FBP1 | P09467 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985885 | 0.80 | LMNA (0.55) | GLO1FBP1NFE2L2LMNAKMT2A | |
| SCHEMBL10507269 | 0.77 | GLO1 (0.68) | GLO1FBP1NFE2L2LMNAKMT2A | |
| SCHEMBL10511400 | 0.77 | GLO1 (0.68) | GLO1FBP1NFE2L2LMNAKMT2A | |
| SCHEMBL10983993 | 0.76 | GLO1 (0.66) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL8540762 | 0.76 | CYP1A2 (0.58) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL8540758 | 0.76 | CYP1A2 (0.58) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL6771050 | 0.75 | GLO1 (0.73) | GLO1FBP1NFE2L2LMNAKMT2A | |
| SCHEMBL11664581 | 0.74 | FBP1 (0.69) | GLO1FBP1NFE2L2LMNAKMT2A | |
| SCHEMBL8028846 | 0.74 | GLO1 (1.00) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9656164 | 0.74 | FBP1 (0.69) | GLO1FBP1NFE2L2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001769-A1 | Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |