Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.38 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.38 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.38 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529143 | 0.77 | NLRP3 (0.45) | LMNANAAANLRP3DGKAMAPT | |
| SCHEMBL11525401 | 0.73 | NLRP3 (0.39) | NLRP3DGKAEPHX2 | |
| SCHEMBL11594010 | 0.72 | ALOX15 (0.41) | ALOX15KMT2ASMN1; SMN2LMNANAAA | |
| SCHEMBL6072443 | 0.67 | PRKCA (0.43) | KMT2ASMN1; SMN2LMNANAAAPOLM | |
| SCHEMBL11528557 | 0.67 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL10407328 | 0.66 | KDM4E (0.68) | ALOX15KMT2ALMNAPOLMPOLK | |
| SCHEMBL10407329 | 0.66 | KMT2A (0.65) | ALOX15KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL15548035 | 0.65 | KMT2A (0.66) | ALOX15KMT2ASMN1; SMN2LMNAPOLM | |
| SCHEMBL10571781 | 0.65 | KMT2A (0.66) | ALOX15KMT2ASMN1; SMN2LMNAPOLM | |
| SCHEMBL15548290 | 0.65 | KMT2A (0.66) | ALOX15KMT2ASMN1; SMN2LMNAPOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132750-A | RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES | SHOWA DENKO K.K. (JP) | 1979-01-02 | — | — | US | disclosed |
| US-3959234-A | CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-05-25 | — | — | US | disclosed |