Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565422 | 0.89 | F9 (0.46) | PPARGSLC22A12PPARACNR2MMP2 | |
| SCHEMBL11567624 | 0.89 | POLB (0.44) | PPARGSLC22A12UTS2RF9F10 | |
| SCHEMBL11568422 | 0.89 | POLB (0.44) | PPARGSLC22A12UTS2RF9F10 | |
| SCHEMBL11562673 | 0.89 | PPARG (0.66) | PPARGSLC22A12PPARAF9F10 | |
| SCHEMBL11563520 | 0.88 | PPARG (0.69) | PPARGSLC22A12PPARAF9F10 | |
| SCHEMBL11565230 | 0.86 | PPARG (0.45) | PPARGSLC22A12PPARAF9F10 | |
| SCHEMBL11561168 | 0.84 | PPARG (0.51) | PPARGSLC22A12PPARAUTS2RF9 | |
| SCHEMBL11564504 | 0.84 | PPARG (0.51) | PPARGSLC22A12PPARAUTS2RF9 | |
| SCHEMBL14541455 | 0.82 | PPARG (0.75) | PPARGSLC22A12PPARACNR2F9 | |
| SCHEMBL2443487 | 0.82 | PPARG (0.75) | PPARGSLC22A12PPARACNR2F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |