Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561168 | 1.00 | PPARG (0.51) | PPARGPPARAF9F10UTS2R | |
| SCHEMBL11565422 | 0.94 | F9 (0.46) | PPARGPPARAF9F10SLC22A12 | |
| SCHEMBL11563916 | 0.93 | MAPK1 (0.50) | PPARGPPARAMAPK1PGRACACB | |
| SCHEMBL11566988 | 0.89 | F9 (0.51) | PPARGPPARAF9F10UTS2R | |
| SCHEMBL11568618 | 0.88 | F9 (0.48) | PPARGPPARAF9F10UTS2R | |
| SCHEMBL11565802 | 0.88 | ACACB (0.52) | PPARGPPARAMAPK1ACACB | |
| SCHEMBL11565230 | 0.88 | PPARG (0.45) | PPARGPPARAF9F10SLC22A12 | |
| SCHEMBL11568456 | 0.86 | F9 (0.46) | PPARGPPARAF9F10UTS2R | |
| SCHEMBL11638373 | 0.86 | F9 (0.45) | PPARGPPARAF9F10UTS2R | |
| SCHEMBL11565502 | 0.85 | PPARG (0.60) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |