Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561168 | 0.88 | PPARG (0.51) | ACACBPPARGPPARAMAPK1 | |
| SCHEMBL11564504 | 0.88 | PPARG (0.51) | ACACBPPARGPPARAMAPK1 | |
| SCHEMBL11565422 | 0.85 | F9 (0.46) | L3MBTL1PPARGPPARAFNTAFNTB | |
| SCHEMBL11563916 | 0.81 | MAPK1 (0.50) | ACACBLTA4HPPARGPPARANPC1 | |
| SCHEMBL11597904 | 0.80 | PPARG (0.53) | FFAR1PPARGPPARANR4A2 | |
| SCHEMBL6509628 | 0.80 | LTA4H (0.51) | LTA4HFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11568618 | 0.80 | F9 (0.48) | PPARGPPARANPC1RAB9AMEN1 | |
| SCHEMBL11565230 | 0.79 | PPARG (0.45) | L3MBTL1PPARGPPARAFNTAFNTB | |
| SCHEMBL5389840 | 0.79 | PPARG (0.65) | LTA4HPPARGPPARANR4A2PPARD | |
| SCHEMBL13924239 | 0.79 | ALDH1A1 (0.44) | LMNAL3MBTL1LTA4HFFAR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |