SCHEMBL11564591

SCHEMBL11564591

CCCCN(C(=O)C(C)OC(C)=O)c1ccn(C)n1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.36
HDAC1 Q13547 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
JMJD6 Q6NYC1 4/20 0.34
CYP19A1 P11511 3/20 0.33
MLYCD O95822 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ADRB2 P07550 1/20 0.32
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11562204 0.85 MLYCD (0.45) CTSKHDAC1TRPM8JMJD6CYP19A1
SCHEMBL11565645 0.81 HDAC1 (0.41) HDAC1TRPM8JMJD6CYP19A1MLYCD
SCHEMBL11563199 0.80 HDAC1 (0.42) CTSKHDAC1TRPM8JMJD6CYP19A1
SCHEMBL11564127 0.76 HDAC1 (0.45) HDAC1TRPM8JMJD6CYP19A1MLYCD
SCHEMBL11559018 0.74 S1PR1 (0.47) HDAC1MLYCDALDH1A1ADRB2
SCHEMBL9233571 0.73 OPRM1 (0.42) HDAC1TRPM8JMJD6CYP19A1ALDH1A1
SCHEMBL11560800 0.73 CYP3A4 (0.41) HDAC1TRPM8JMJD6CYP19A1MLYCD
SCHEMBL11560805 0.73 CYP3A4 (0.41) HDAC1TRPM8JMJD6CYP19A1MLYCD
SCHEMBL11561112 0.71 HDAC1 (0.48) HDAC1TRPM8JMJD6ALDH1A1LMNA
SCHEMBL11560919 0.71 S1PR1 (0.44) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166123-A ANTIALLERGENS LILLY INDUSTRIES LIMITED (GB) 1979-08-28 US disclosed