Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564127 | 0.94 | HDAC1 (0.45) | HDAC1ELANETRPM8MLYCDJMJD6 | |
| SCHEMBL11562204 | 0.84 | MLYCD (0.45) | HDAC1TRPM8MLYCDJMJD6CYP19A1 | |
| SCHEMBL11559018 | 0.83 | S1PR1 (0.47) | HDAC1MLYCDALDH1A1HTTS1PR1 | |
| SCHEMBL11559929 | 0.83 | HDAC1 (0.46) | HDAC1TRPM8JMJD6LMNAALDH1A1 | |
| SCHEMBL9233571 | 0.82 | OPRM1 (0.42) | HDAC1TRPM8JMJD6CYP19A1LMNA | |
| SCHEMBL11560800 | 0.82 | CYP3A4 (0.41) | HDAC1TRPM8MLYCDJMJD6CYP19A1 | |
| SCHEMBL11560805 | 0.82 | CYP3A4 (0.41) | HDAC1TRPM8MLYCDJMJD6CYP19A1 | |
| SCHEMBL11564591 | 0.81 | CTSK (0.36) | HDAC1TRPM8MLYCDJMJD6CYP19A1 | |
| SCHEMBL11561112 | 0.80 | HDAC1 (0.48) | HDAC1TRPM8JMJD6LMNAALDH1A1 | |
| SCHEMBL11560919 | 0.80 | S1PR1 (0.44) | LMNAKDM4EALDH1A1SMN1; SMN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166123-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1979-08-28 | — | — | US | disclosed |