Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560207 | 0.87 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL11558397 | 0.87 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL11558186 | 0.87 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL29960816 | 0.81 | HTR2A (0.37) | HTR2AHTR2CHTR2BTAAR1 | |
| Hydrochloric Acid SCHEMBL29960697 | 0.80 | TAAR1 (0.37) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL10371550 | 0.76 | LMNA (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL2226246 | 0.73 | HTR6 (0.58) | HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL20045526 | 0.73 | HTR6 (0.58) | HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL17123749 | 0.73 | HTR2A (0.38) | HTR2AHTR2C | |
| SCHEMBL11373905 | 0.73 | HTR2A (0.44) | HTR2AHTR2CHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132710-A | DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS | AYERST, MCKENNA AND HARRISON, LTD. (CA) | 1979-01-02 | — | — | US | disclosed |
| US-4132710-A | DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS | AYERST, MCKENNA AND HARRISON, LTD. (CA) | 1979-01-02 | — | — | US | disclosed |