Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29960697 | 0.98 | TAAR1 (0.37) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL11558397 | 0.91 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1CYP2D6 | |
| SCHEMBL11558186 | 0.91 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1CYP2D6 | |
| SCHEMBL11560207 | 0.91 | HTR2C (0.39) | HTR2AHTR2CHTR2BTAAR1CYP2D6 | |
| SCHEMBL11564664 | 0.81 | HTR6 (0.40) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL10371550 | 0.80 | LMNA (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL11638682 | 0.75 | PRCP (0.46) | CYP2D6 | |
| SCHEMBL17123749 | 0.71 | HTR2A (0.38) | HTR2AHTR2CCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28748526 | 0.69 | PRCP (0.46) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL11561852 | 0.68 | HTR2C (0.50) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |