Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564209 | 0.89 | HTT (0.46) | SMN1; SMN2MEN1KMT2APOLBTDP1 | |
| SCHEMBL23147211 | 0.88 | PTGS2 (0.45) | KMT2AGRM1L3MBTL1HCAR1LMNA | |
| SCHEMBL11562309 | 0.88 | RAB9A (0.48) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL11559116 | 0.87 | RAB9A (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11560097 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL11565675 | 0.84 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11560398 | 0.81 | MEN1 (0.51) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29812449 | 0.75 | PTGS2 (0.44) | GRM1L3MBTL1HCAR1ESR1ESR2 | |
| SCHEMBL11564507 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11560437 | 0.74 | RAB9A (0.46) | SMN1; SMN2NPC1RAB9AGRM1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147528-A | 6-Oxopyrimidine plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-04-03 | — | — | US | disclosed |