Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407866 | 0.81 | POLB (0.54) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL29167457 | 0.80 | L3MBTL1 (0.43) | L3MBTL1KCNH3CNR2CNR1TLR8 | |
| SCHEMBL10408672 | 0.80 | LIPG (0.49) | ADRA2BADRA2CL3MBTL1KCNH3POLB | |
| SCHEMBL10408718 | 0.80 | POLB (0.53) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL3248990 | 0.80 | POLB (0.53) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL10407954 | 0.80 | POLB (0.53) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL1724131 | 0.78 | L3MBTL1 (0.51) | L3MBTL1KCNH3CNR2CNR1TLR8 | |
| SCHEMBL6693838 | 0.78 | HCAR3 (0.38) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL10408667 | 0.78 | LIPG (0.47) | L3MBTL1KCNH3POLBCNR2CNR1 | |
| SCHEMBL4557996 | 0.78 | LIPG (0.51) | L3MBTL1KCNH3POLBCNR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | claimed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |