SCHEMBL11565101

SCHEMBL11565101

CC(C)(CCc1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TTR P02766 2/20 0.37
CYP3A4 P08684 2/20 0.37
RECQL P46063 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2C9 P11712 3/20 0.37
CYP2D6 P10635 1/20 0.37
THRB P10828 2/20 0.34
CYP2C19 P33261 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP1A2 P05177 2/20 0.33
ALOX15 P16050 2/20 0.33
ALOX12 P18054 2/20 0.33
NPC1 O15118 2/20 0.33
ACLY P53396 1/20 0.33
DBH P09172 1/20 0.33
NR1I2 O75469 1/20 0.32
NR1H2 P55055 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756848 0.86 PTGS1 (0.37) TSHRHSD17B10CYP3A4RECQLALDH1A1
SCHEMBL143803 0.77 PTGS1 (0.47) TTRCYP3A4ALDH1A1CYP2C9CYP2D6
SCHEMBL9070172 0.76 CNR2 (0.51) CNR1ESR1
SCHEMBL7885118 0.75 HSD17B10 (0.55) TSHRHSD17B10TTRCYP3A4RECQL
SCHEMBL9070169 0.75 SHBG (0.50) TSHRHSD17B10TTRCYP3A4RECQL
SCHEMBL10538022 0.74 TSHR (0.53) TSHRHSD17B10TTRCYP3A4RECQL
SCHEMBL11468054 0.73 PTGS1 (0.43) TSHRHSD17B10CYP3A4RECQLALDH1A1
SCHEMBL445337 0.71 HSD17B10 (0.46) TSHRHSD17B10TTRCYP3A4RECQL
SCHEMBL2415959 0.71 HSD17B10 (0.50) TSHRHSD17B10TTRCYP3A4RECQL
SCHEMBL6321695 0.71 GABRA1 (0.52) TSHRHSD17B10TTRCYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140730-A FLAME RESISTANT, ELECTRICAL INSULATOR, MIXTURE OF HALOGENATED POLYCARBONATE AND BISPHENOL A POLYCARBONATE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed