SCHEMBL445337

SCHEMBL445337

CCCc1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
TSHR P16473 3/20 0.46
CYP3A4 P08684 2/20 0.46
TTR P02766 2/20 0.46
ALDH1A1 P00352 1/20 0.46
RECQL P46063 1/20 0.46
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
THRB P10828 1/20 0.42
ESR1 P03372 1/20 0.42
CYP2C9 P11712 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP1A2 P05177 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
PTGS2 P35354 3/20 0.40
CYP2D6 P10635 1/20 0.39
NPC1 O15118 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10415447 0.87 PTGS2 (0.43) TSHRCYP3A4TTRALDH1A1CNR1
SCHEMBL7719773 0.86 NPC1 (0.55) HSD17B10TSHRCYP3A4TTRALDH1A1
SCHEMBL28787872 0.86 ALDH1A1 (0.45) HSD17B10TSHRCYP3A4TTRALDH1A1
SCHEMBL5182611 0.86 CNR1 (0.37) HSD17B10TSHRCYP3A4TTRALDH1A1
SCHEMBL7885118 0.85 HSD17B10 (0.55) HSD17B10TSHRCYP3A4TTRALDH1A1
SCHEMBL10981904 0.85 PTGS2 (0.61) HSD17B10CYP3A4ALDH1A1ESR1HIF1A
SCHEMBL29079401 0.83 PTGS2 (0.62) HSD17B10CYP3A4ALDH1A1ESR1HIF1A
SCHEMBL29079400 0.83 PTGS2 (0.62) HSD17B10CYP3A4ALDH1A1ESR1HIF1A
SCHEMBL9389815 0.83 PTGS2 (0.62) HSD17B10CYP3A4ALDH1A1ESR1HIF1A
SCHEMBL9070242 0.83 PTGS2 (0.62) HSD17B10CYP3A4ALDH1A1ESR1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 895 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117996078-A Battery binder, preparation method thereof and lithium ion battery 深圳市研一新材料有限责任公司 2024-05-07 CN claimed
US-11884777-B2 Diol compound, polycarbonate, and preparation method of the same LG CHEM, LTD. (KR) 2024-01-30 US claimed
CN-113412257-B Diol compound, polycarbonate and process for producing the same 株式会社LG化学 2023-09-29 CN claimed
CN-116406393-A Polycarbonate copolymer and method for producing the same 株式会社LG化学 2023-07-07 CN claimed
CN-112469684-B Diol compound, polycarbonate and process for producing the same 株式会社LG化学 2023-06-30 CN claimed
CN-116323801-A Polycarbonate composite composition and preparation method thereof 株式会社LG化学 2023-06-23 CN claimed
CN-116144029-A Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华材料科技有限公司 2023-05-23 CN claimed
CN-116096781-A Polycarbonate and process for producing the same 株式会社LG化学 2023-05-09 CN claimed
CN-112654659-B Polycarbonate and method for producing same 株式会社LG化学 2023-01-20 CN claimed
CN-112739744-B Polycarbonate and method for producing same 株式会社LG化学 2023-01-20 CN claimed
EP-1902106-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS Henkel Corporation (US) 2008-03-26 EP claimed
WO-2007008199-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS HENKEL CORPORATION (US) 2007-01-18 WO claimed
US-20050031565-A1 Deodorant cosmetic composition comprising at least one semicrystalline polymer EVONIK DEGUSSA GMBH (DE) 2005-02-10 US claimed
EP-1360221-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-12 EP claimed
EP-1358246-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-05 EP claimed
EP-1358247-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-05 EP claimed
WO-2002055585-A2 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2002-07-18 WO claimed
WO-2002055583-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
WO-2002055584-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed
US-4065517-A POLYPHOSPHONATES NISSAN CHEMICAL INDUSTRIES LTD. (JA) 1977-12-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050031565-A1 Deodorant cosmetic composition comprising at least one semicrystalline polymer DEK, CUTA, DSG1 HSD17B10 685/4885TSHR 3299/4885CYP3A4 2793/4885
US-11884777-B2 Diol compound, polycarbonate, and preparation method of the same PKD1, CYP19A1, CYP17A1 HSD17B10 168/4885TSHR 4441/4885CYP3A4 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.