Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | FABP2 | P12104 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568731 | 0.93 | PPARA (0.60) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11600781 | 0.87 | PPARA (0.57) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11601202 | 0.87 | PPARG (0.54) | PPARAMEN1KMT2APPARGPPARD | |
| SCHEMBL11600576 | 0.82 | PPARA (0.62) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11602527 | 0.82 | PPARA (0.58) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11639887 | 0.81 | PPARA (0.47) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11598113 | 0.81 | PPARA (0.55) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11595598 | 0.80 | PPARA (0.55) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11595888 | 0.79 | PPARA (0.54) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11566652 | 0.78 | PPARA (0.49) | PPARACYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |