Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595828 | 0.92 | PPARA (0.53) | PPARAMEN1KMT2APPARGNPC1 | |
| SCHEMBL11600781 | 0.88 | PPARA (0.57) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11568731 | 0.87 | PPARA (0.60) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11598113 | 0.84 | PPARA (0.55) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL2499574 | 0.83 | PPARA (0.44) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11600576 | 0.83 | PPARA (0.62) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11565233 | 0.81 | PPARA (0.53) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11597279 | 0.80 | PPARD (0.50) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11596698 | 0.79 | PKM (0.45) | PPARAMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11602031 | 0.79 | PPARA (0.61) | PPARAMEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |