Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.54 |
| ▸ | FABP2 | P12104 | 2/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600576 | 0.95 | PPARA (0.62) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11568731 | 0.94 | PPARA (0.60) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11602031 | 0.91 | PPARA (0.61) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11639887 | 0.88 | PPARA (0.47) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11565233 | 0.87 | PPARA (0.53) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11598113 | 0.87 | PPARA (0.55) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11601984 | 0.85 | PPARA (0.54) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11601202 | 0.85 | PPARG (0.54) | PPARAMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL11601217 | 0.84 | PPARG (0.57) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL5691818 | 0.84 | PPARG (0.61) | PPARACYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072754-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-07 | — | — | US | claimed |
| US-4072754-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-02-07 | — | — | US | disclosed |