Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.64 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565561 | 0.92 | HCAR3 (0.66) | HCAR3USP30CXCR1CXCR2RXRA | |
| SCHEMBL26835972 | 0.91 | USP30 (0.53) | HCAR3USP30GAACXCR1CXCR2 | |
| SCHEMBL11560456 | 0.88 | HCAR3 (0.61) | HCAR3USP30CXCR1CXCR2RXRA | |
| SCHEMBL11566151 | 0.85 | HCAR3 (0.69) | HCAR3USP30LDHARXRAMAPT | |
| SCHEMBL1720417 | 0.84 | HCAR3 (0.60) | HCAR3CXCR1CXCR2TRPM8LDHA | |
| SCHEMBL11563144 | 0.83 | HCAR3 (0.66) | HCAR3RXRAPKMHDAC1 | |
| SCHEMBL11566168 | 0.82 | HCAR3 (0.62) | HCAR3CXCR1CXCR2TRPM8LDHA | |
| SCHEMBL11564474 | 0.82 | HCAR3 (0.54) | HCAR3USP30GAACXCR1CXCR2 | |
| SCHEMBL11564059 | 0.82 | HCAR3 (0.64) | HCAR3RXRAPKMHDAC1 | |
| SCHEMBL11564719 | 0.81 | HCAR3 (0.63) | HCAR3RXRAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |