Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563144 | 0.92 | HCAR3 (0.66) | HCAR3PKMRXRAHDAC1AOC3 | |
| SCHEMBL11564059 | 0.91 | HCAR3 (0.64) | HCAR3PKMRXRAHDAC1 | |
| SCHEMBL11564719 | 0.89 | HCAR3 (0.63) | HCAR3PKMRXRA | |
| SCHEMBL11564881 | 0.89 | HCAR3 (0.66) | HCAR3PKMRXRAAOC3RXRB | |
| SCHEMBL11565525 | 0.85 | HCAR3 (0.61) | HCAR3PKMRXRAHDAC1AOC3 | |
| SCHEMBL11565320 | 0.85 | HCAR3 (0.64) | HCAR3PKMRXRAHDAC1LDHA | |
| SCHEMBL11564788 | 0.79 | PKM (0.62) | HCAR3PKMAOC3POLBTAAR1 | |
| SCHEMBL1906313 | 0.79 | HCAR3 (0.77) | HCAR3RXRAAOC3LDHARXRB | |
| SCHEMBL24422211 | 0.78 | HCAR3 (0.71) | HCAR3P4HA1P4HTMMAPT | |
| SCHEMBL6257695 | 0.78 | PTGER1 (0.50) | HCAR3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |