Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641094 | 0.81 | POLB (0.55) | HSD11B1MGLLEPHX1MEN1KMT2A | |
| SCHEMBL377906 | 0.81 | DRD4 (0.64) | DRD4ACHEBACE1BCHECXCR4 | |
| SCHEMBL28292405 | 0.80 | HSD11B1 (0.55) | HSD11B1MGLLCYP2C9CYP2C19MAPK14 | |
| SCHEMBL29238649 | 0.78 | DRD4 (0.61) | DRD4ACHEBACE1BCHEFABP6 | |
| SCHEMBL28292403 | 0.77 | HSD11B1 (0.53) | HSD11B1MGLLEPHX1KMT2A | |
| SCHEMBL11566253 | 0.76 | MGLL (0.60) | HSD11B1MGLLMEN1KMT2A | |
| SCHEMBL18640371 | 0.76 | EPHX2 (0.60) | DRD4ACHEBACE1BCHEFABP6 | |
| SCHEMBL4080791 | 0.76 | FABP6 (0.60) | DRD4ACHEBACE1BCHECXCR4 | |
| SCHEMBL16269315 | 0.75 | ACHE (0.60) | DRD4ACHEBACE1BCHEFABP6 | |
| SCHEMBL1189971 | 0.75 | ACHE (0.60) | DRD4ACHEBACE1BCHEFABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | disclosed |