Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280742 | 0.90 | TSHR (0.44) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL4333002 | 0.85 | TSHR (0.40) | TSHRPPARDTP53TDP1 | |
| SCHEMBL11051153 | 0.79 | POLB (0.39) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL8302722 | 0.76 | TSHR (0.39) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL11340245 | 0.75 | GAA (0.44) | TSHRTDP1CA12CA1CA2 | |
| SCHEMBL337596 | 0.74 | TSHR (0.48) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL28862969 | 0.72 | TSHR (0.46) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL2236600 | 0.71 | TSHR (0.44) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL27617158 | 0.70 | L3MBTL1 (0.30) | — | |
| SCHEMBL17937991 | 0.70 | TSHR (0.40) | TSHRPPARDTP53TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | disclosed |