Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280742 | 0.85 | TSHR (0.44) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL15438595 | 0.81 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL337596 | 0.81 | TSHR (0.48) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL28862969 | 0.79 | TSHR (0.46) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11565404 | 0.76 | TSHR (0.40) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL15439167 | 0.75 | TSHR (0.39) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL6669420 | 0.75 | TSHR (0.46) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL2236600 | 0.73 | TSHR (0.44) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL17937991 | 0.73 | TSHR (0.40) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL1331297 | 0.72 | TSHR (0.48) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912511-A1 | 5-INDOLYL-2,4-PENTADIENOIC ACID DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | Smithkline Beecham S.p.A. (IT) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001423-A1 | 5-INDOLYL-2,4-PENTADIENOIC ACID DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-01-15 | — | — | WO | disclosed |