SCHEMBL1156561

SCHEMBL1156561

CCCCCCCCCCc1c(Br)sc2c1sc1c2sc2c3sccc3sc21

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12873851 1.00 GPR35 (0.53) GPR35
SCHEMBL1156691 0.99 GPR35 (0.54) GPR35
SCHEMBL28041468 0.88 GPR35 (0.62) GPR35
SCHEMBL28041472 0.88 GPR35 (0.62) GPR35
SCHEMBL28784135 0.88 GPR35 (0.62) GPR35
SCHEMBL1157428 0.84 GPR35 (0.54) GPR35
SCHEMBL12704412 0.84 GPR35 (0.54) GPR35
SCHEMBL1459443 0.83 GPR35 (0.43) GPR35
SCHEMBL10021737 0.83 GPR35 (0.43) GPR35
SCHEMBL10021730 0.83 GPR35 (0.43) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2308882-B1 Fused thiophenes and uses thereof CORNING INC (US) 2018-06-13 EP disclosed
EP-2773646-B1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2016-06-15 EP disclosed
EP-2129678-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2015-05-27 EP disclosed
US-8846855-B2 Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2014-09-30 US disclosed
EP-2773687-A1 FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF Corning Inc. (US) 2014-09-10 EP disclosed
EP-2773646-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF Corning Incorporated (US) 2014-09-10 EP disclosed
EP-1799688-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2013-06-19 EP disclosed
WO-2013066973-A1 FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED (US) 2013-05-10 WO disclosed
WO-2013066732-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED (US) 2013-05-10 WO disclosed
US-20130109821-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED 2013-05-02 US disclosed
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2011-02-17 US disclosed
US-7838623-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-11-23 US disclosed
US-7705108-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-04-27 US disclosed
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2010-01-14 US disclosed
EP-2129678-A2 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED (US) 2009-12-09 EP disclosed
WO-2008106019-A2 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED (US) 2008-09-04 WO disclosed
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof CORNING INCORPORATED 2007-11-15 US disclosed
US-20070161776-A1 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED 2007-07-12 US disclosed
EP-1799688-A2 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC. (US) 2007-06-27 EP disclosed
WO-2006031893-A2 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INCORPORATED (US) 2006-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4429/4885
US-20130109821-A1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF TST, TPMT, TPR GPR35 4231/4885
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4520/4885
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof TPMT, TST, TYMP GPR35 4429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.