SCHEMBL11565759

SCHEMBL11565759

Cc1c(CO)cc([N+](=O)[O-])c(Cl)c1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.42
TSHR P16473 6/20 0.39
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HIF1A Q16665 1/20 0.38
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
VCAM1 P19320 1/20 0.38
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
IMPDH2 P12268 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565097 0.88 GPR35 (0.40) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11600578 0.87 GRIN2D (0.43) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11319450 0.83 GRIN2D (0.40) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11564938 0.82 ALOX15 (0.40) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11562945 0.82 GPR35 (0.36) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11561732 0.81 TSHR (0.42) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11332666 0.80 TSHR (0.36) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11564941 0.79 ALDH1A1 (0.38) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL8649537 0.78 CYP1A2 (0.52) GPR35TSHRALDH1A1TDP1CYP3A4
SCHEMBL11049725 0.78 TSHR (0.50) GPR35TSHRALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180679-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1979-12-25 US disclosed