Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564635 | 0.84 | CNR2 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL11564632 | 0.84 | LMNA (0.42) | ALDH1A1CYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL29785793 | 0.82 | TRPV4 (0.55) | ALDH1A1TRPV4SMN1; SMN2TSHRLMNA | |
| SCHEMBL2494766 | 0.82 | TRPV4 (0.55) | ALDH1A1TRPV4SMN1; SMN2TSHRLMNA | |
| SCHEMBL8187498 | 0.73 | TRPV4 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2C19TRPV4 | |
| SCHEMBL6176193 | 0.71 | TRPV4 (0.50) | ALDH1A1TRPV4SMN1; SMN2TSHRLMNA | |
| SCHEMBL8189395 | 0.71 | TRPV4 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19TRPV4 | |
| SCHEMBL4493224 | 0.71 | TRPV4 (0.49) | ALDH1A1TRPV4SMN1; SMN2TSHRLMNA | |
| SCHEMBL12627515 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1CYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL1713241 | 0.71 | TRPV4 (0.49) | TRPV4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173630-A | N2 Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-11-06 | — | — | US | disclosed |