Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415480 | 0.91 | KCNA3 (0.57) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10883271 | 0.83 | MAPT (0.52) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9264626 | 0.83 | MAPT (0.74) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL491473 | 0.81 | CA1 (0.39) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4482378 | 0.80 | KCNA3 (0.47) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3862572 | 0.80 | MAPT (0.44) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1764840 | 0.80 | ADORA2A (0.66) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| Formaldehyde SCHEMBL28708546 | 0.80 | TOP1 (0.38) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28569052 | 0.79 | MAPT (0.68) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10927218 | 0.79 | ADORA2A (0.60) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169897-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4059702-A | ANTIVIRAL | RICHARDSON-MERRELL INC. (US) | 1977-11-22 | — | — | US | disclosed |