SCHEMBL6415480

SCHEMBL6415480

O=C1c2ccccc2C(=O)c2c(Oc3cccc4c3C(=O)c3ccccc3C4=O)cccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.57
ADORA2A P29274 2/20 0.55
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
CDC25B P30305 1/20 0.52
MAPT P10636 8/20 0.50
ALDH1A1 P00352 7/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
RAB9A P51151 4/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
EGFR P00533 4/20 0.50
MAPK1 P28482 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
NPC1 O15118 2/20 0.50
KDM4E B2RXH2 2/20 0.50
PABPC1 P11940 1/20 0.50
USP2 O75604 1/20 0.50
DUSP3 P51452 1/20 0.50
NSD2 O96028 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565971 0.91 MAPT (0.50) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL1764840 0.88 ADORA2A (0.66) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL3766191 0.87 ADORA2A (0.61) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL4482378 0.84 KCNA3 (0.47) KCNA3ADORA2AMEN1KMT2AMAPT
SCHEMBL11581927 0.83 MAPT (0.44) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL10927218 0.83 ADORA2A (0.60) KCNA3ADORA2AMEN1KMT2AMAPT
SCHEMBL1893344 0.83 ADORA2A (0.57) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL183075 0.83 MAPT (0.54) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL612831 0.83 MAPT (0.74) KCNA3ADORA2AMEN1KMT2ACDC25B
SCHEMBL4462792 0.83 ALDH1A1 (0.62) KCNA3ADORA2AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677107-A PHOTOHARDENABLE FILM WITH PHOTORESPONSIVE AGENT; IRRADIATING SELECTIVE PORTIONS OF CROSS-SECTIONAL PATTERNS THAT ARE TO BE COLORED DIFFERENTLY SPECTRA GROUP LIMITED, INC. (US) 1997-10-14 US claimed
CN-101336268-B Weatherable resin compositions with low heat buildup and methods GEN ELECTRIC 2013-06-12 CN disclosed
CN-100543097-C A kind of have low dismounting force moment fire resistant anaerobic adhesive and preparation method thereof HEILONGJIANG INST OF PETROCHEM (CN) 2009-09-23 CN disclosed
CN-101336268-A Weatherable resin compositions with low heat buildup and methods GEN ELECTRIC (US) 2008-12-31 CN disclosed
CN-101058699-A Fire resistant anaerobic adhesive with low dismounting force moment and preparation method thereof HEILONGJIANG INST OF PETROCHEM (CN) 2007-10-24 CN disclosed
US-6919453-B1 Colorant compositions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2005-07-19 US disclosed
JP-2003104930-A METHOD FOR PRODUCING 9,10-ANTHRAQUINONYL ETHER KAWASAKI KASEI CHEM LTD 2003-04-09 JP disclosed
CN-1063212-C Phtotpolymerizable resin material composition SHARP KK (JP) 2001-03-14 CN disclosed
US-5942370-A MULTICOLOR PHOTOPOLYMERIZATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-24 US disclosed
US-5677107-A PHOTOHARDENABLE FILM WITH PHOTORESPONSIVE AGENT; IRRADIATING SELECTIVE PORTIONS OF CROSS-SECTIONAL PATTERNS THAT ARE TO BE COLORED DIFFERENTLY SPECTRA GROUP LIMITED, INC. (US) 1997-10-14 US disclosed
CN-1131177-A Phtotpolymerizable resin material composition SHARP KK (JP) 1996-09-18 CN disclosed
US-4797347-A Process for producing electrically conductive coating CIBA-GEIGY CORPORATION (US) 1989-01-10 US disclosed
US-4677155-A Anthroquinonyl photosensitive polymers CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4014647-A DISPERSE DYES CONTAINING SULFONAMIDE GROUPS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-3983145-A Use of alpha-di(lower alkoxy) anthraquinones in the synthesis of Alizarin Saphirols TOMS RIVER CHEMICAL CORPORATION (US) 1976-09-28 US disclosed
US-3980427-A MONOAZO OR DISAZO DYE, HALOGENATED HYDROCARBON BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed