Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110858 | 0.73 | — | — | |
| SCHEMBL577897 | 0.71 | MAOA (0.42) | TRPA1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL367855 | 0.68 | TRPA1 (0.52) | TRPA1KDM4EMEN1ALDH1A1MAPT | |
| Dibenzo[B,F]Oxepine SCHEMBL1650179 | 0.68 | MEN1 (0.64) | TRPA1KDM4EMEN1ALDH1A1MAPT | |
| Arsenic SCHEMBL28557236 | 0.66 | — | — | |
| SCHEMBL4749318 | 0.66 | TRPA1 (0.50) | TRPA1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22635712 | 0.65 | GAA (0.33) | MAPT | |
| SCHEMBL22635713 | 0.65 | GAA (0.33) | MAPT | |
| SCHEMBL125113 | 0.63 | MAOA (0.56) | TRPA1KDM4EMAOAMAOBALOX5 | |
| SCHEMBL3102452 | 0.63 | MAOA (0.56) | TRPA1KDM4EMAOAMAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180559-A | Coated 1-(2-chlorodibenzo[b,f]oxepin-10-yl)-4-methylpiperazine compositions | RICHARDSON-MERRELL INC. (US) | 1979-12-25 | — | — | US | disclosed |