Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | GNRHR | P30968 | 1/20 | 0.54 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 10/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150398 | 0.91 | CCKBR (0.62) | PTGS1CXCL8CCKBR | |
| SCHEMBL30339999 | 0.89 | CXCL8 (0.60) | CXCL8CCKBR | |
| SCHEMBL23928719 | 0.88 | CCKBR (0.67) | CXCL8CCKBR | |
| SCHEMBL29349773 | 0.88 | CCKBR (0.67) | CXCL8CCKBR | |
| SCHEMBL29362913 | 0.88 | CCKBR (0.67) | CXCL8CCKBR | |
| SCHEMBL30435302 | 0.86 | CXCL8 (0.60) | CXCL8CCKBR | |
| SCHEMBL11566717 | 0.82 | CCKBR (0.53) | CCKBR | |
| SCHEMBL29408673 | 0.79 | CCKBR (0.70) | CCKBR | |
| SCHEMBL31332293 | 0.78 | PTGS1 (0.61) | PTGS1GNRHRABCC2KISS1R | |
| SCHEMBL11589771 | 0.78 | GNRHR (0.63) | PTGS1GNRHRABCC2CXCL8KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164571-A | Medicament which antagonizes the action of gastrin and related polypeptides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1979-08-14 | — | — | US | claimed |
| US-4164571-A | Medicament which antagonizes the action of gastrin and related polypeptides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1979-08-14 | — | — | US | disclosed |