SCHEMBL29408673

SCHEMBL29408673

CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 12/20 0.70
▸ NMBR P28336 1/20 0.61
▸ GRPR P30550 1/20 0.61
▸ CXCR4 P61073 2/20 0.61
▸ GLP1R P43220 4/20 0.59
▸ GIPR P48546 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29150398 0.88 CCKBR (0.62) CCKBR
SCHEMBL30305898 0.87 CCKBR (0.83) CCKBR
SCHEMBL30533211 0.86 CCKBR (0.83) CCKBR
SCHEMBL23928719 0.86 CCKBR (0.67) CCKBR
SCHEMBL29349773 0.86 CCKBR (0.67) CCKBR
SCHEMBL29362913 0.86 CCKBR (0.67) CCKBR
SCHEMBL31182464 0.85 GLP1R (0.62) CXCR4GLP1RGIPR
SCHEMBL29414561 0.85 CCKBR (0.80) CCKBR
SCHEMBL31015845 0.85 CCKBR (0.82) CCKBR
SCHEMBL30951444 0.85 CCKBR (0.82) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605447-B2 Stable formulations for radionuclide complexes ITM SOLUCIN GMBH (DE) 2026-04-21 — — US disclosed
US-20250170243-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2025-05-29 — — US disclosed
US-20240374732-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2024-11-14 — — US disclosed
US-20230414796-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotope Technologies Munich SE (DE) 2023-12-28 — — US disclosed
EP-4065176-B1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM ISOTOPE TECH MUNICH SE (DE) 2023-10-11 — — EP disclosed
EP-4218749-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM Isotope Technologies Munich SE (DE) 2023-08-02 — — EP disclosed
EP-3965751-B1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM ISOTOPE TECH MUNICH SE (DE) 2022-12-28 — — EP disclosed
US-20220304964-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2022-09-29 — — US disclosed
CN-114126654-A Para-aminohippuric acid (PAH) as a kidney protective substance 同位素技术慕尼黑有限公司 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605447-B2 Stable formulations for radionuclide complexes EPOR, CD47, PRCP CCKBR 107/4885NMBR 895/4885GRPR 30/4885
US-20250170243-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES SLC40A1, SLC7A11, GYPA CCKBR 1119/4885NMBR 1168/4885GRPR 316/4885
US-20220304964-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE PAH, SLCO1B1, SLCO2B1 CCKBR 1100/4885NMBR 2030/4885GRPR 383/4885
US-20240374732-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES SLC40A1, SLC7A11, GYPA CCKBR 1085/4885NMBR 1129/4885GRPR 324/4885
US-20230414796-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER PAH, VHL, SLC10A6 CCKBR 389/4885NMBR 899/4885GRPR 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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