Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.55 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13991130 | 0.89 | LMNA (0.79) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL145265 | 0.88 | LMNA (0.78) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL29585980 | 0.87 | LMNA (0.77) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL29585688 | 0.85 | LMNA (0.74) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL3408341 | 0.82 | LMNA (0.69) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL11221252 | 0.80 | LMNA (0.67) | LMNAMAPTMEN1KMT2AACHE | |
| SCHEMBL19041261 | 0.80 | LMNA (0.66) | LMNAMAPTMEN1KMT2AKDM4E | |
| Orsellinic Acid SCHEMBL10727043 | 0.79 | CYP3A4 (0.69) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL1129779 | 0.78 | CYP3A4 (0.67) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL11628971 | 0.78 | SLC5A1 (0.71) | LMNAMAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103030619-B | C-crystal-form 5-methyl-7-methoxyiso-flavone and preparation method, pharmaceutical compositions and application of C-crystal-form 5-methyl-7-methoxyiso-flavone | INST MATERIA MEDICA CAMS | 2015-04-22 | — | — | CN | disclosed |
| CN-101591324-B | Three crystal forms of 5-methyl-7-methoxyisoflavone, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS | 2013-07-10 | — | — | CN | disclosed |
| CN-103030619-A | C-crystal-form 5-methyl-7-methoxyiso-flavone and preparation method, pharmaceutical compositions and application of C-crystal-form 5-methyl-7-methoxyiso-flavone | INST MATERIA MEDICA CAMS | 2013-04-10 | — | — | CN | disclosed |
| CN-101591324-A | Three crystal forms of 5-methyl-7-methoxyisoflavone, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS (CN) | 2009-12-02 | — | — | CN | disclosed |
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |