SCHEMBL145265

SCHEMBL145265

O=C(Cc1ccccc1)c1c(O)cc(O)cc1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.78
MAPT P10636 6/20 0.69
GAA P10253 5/20 0.69
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
HPGD P15428 4/20 0.69
CYP3A4 P08684 3/20 0.69
MAPK1 P28482 2/20 0.69
SLC5A1 P13866 2/20 0.69
SLC5A2 P31639 2/20 0.69
PIK3CA P42336 1/20 0.69
CBS P35520 1/20 0.61
PKM P14618 1/20 0.61
ALDH1A1 P00352 2/20 0.54
HSD17B10 Q99714 2/20 0.54
USP2 O75604 1/20 0.54
ALOX15 P16050 1/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566548 0.88 LMNA (1.00) LMNAMAPTGAAMEN1KMT2A
SCHEMBL5036945 0.86 MAPT (0.77) LMNAMAPTGAAMEN1KMT2A
SCHEMBL27697248 0.85 MAPT (0.60) LMNAMAPTGAAMEN1KMT2A
SCHEMBL5034195 0.84 LMNA (0.58) LMNAMAPTGAAMEN1KMT2A
SCHEMBL11628971 0.81 SLC5A1 (0.71) LMNAMAPTGAAMEN1KMT2A
SCHEMBL455029 0.81 SLC5A1 (1.00) LMNAMAPTGAAMEN1KMT2A
SCHEMBL11627675 0.81 SLC5A1 (0.71) LMNAMAPTGAAMEN1KMT2A
SCHEMBL8575394 0.81 MAPT (0.69) LMNAMAPTGAAMEN1KMT2A
SCHEMBL8578359 0.81 MAPT (0.55) LMNAMAPTGAAMEN1KMT2A
SCHEMBL9123733 0.81 LMNA (0.58) LMNAMAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116622664-A Method for generating C-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN claimed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP claimed
CN-103209717-B Lubricious coatings for medical devices BIOINTERACTIONS LTD 2015-04-08 CN claimed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US claimed
EP-2613819-A1 Lubricious coatings for medical devices Biointeractions Ltd. (GB) 2013-07-17 EP claimed
WO-2012032283-A1 Lubricious coatings for medical devices BIOINTERACTIONS LTD (GB) 2012-03-15 WO claimed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US claimed
EP-0245518-A1 ISOFLAVONE DERIVATIVES, SALTS THEREOF, AND ONCOSTATIC AND IMMUNOSUPPRESSIVE AGENTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-11-19 EP claimed
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2025-03-13 US disclosed
CN-119263971-A Preparation method of cyclopentenone compound and salt thereof and application of cyclopentenone compound in treating cerebral apoplexy 中国医学科学院药物研究所 2025-01-07 CN disclosed
CN-116622664-A Method for generating C-glycoside through biocatalysis 湖南师范大学 2023-08-22 CN disclosed
WO-2023278394-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2023-01-05 WO disclosed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
WO-1991016293-A1 IMPROVED PROCESS FOR THE PREPARATION OF KETONE COMPOUNDS CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT Tó utca 1-5 (HU) 1991-10-31 WO disclosed
US-4960908-A ANTIBODY INHIBITOR AND ANTICARCINOGENIC AGENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1990-10-02 US disclosed
US-4841077-A Isoflavone derivatives, and salts thereof, and cancerocidal and immunosuppressive agents containing the same YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1989-06-20 US disclosed
EP-0245518-A1 ISOFLAVONE DERIVATIVES, SALTS THEREOF, AND ONCOSTATIC AND IMMUNOSUPPRESSIVE AGENTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-11-19 EP disclosed
US-4499171-A IN ALKALI SOLUBLE NOVOLAK RESIN JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-02-12 US disclosed
EP-0092444-A2 Positive type photosensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF PGC, SLC5A6, PUF60 LMNA 3387/4885MAPT 3007/4885GAA 544/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 LMNA 289/4885MAPT 1209/4885GAA 2213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.