SCHEMBL1156690

SCHEMBL1156690

O=C(O)Oc1ccccc1-c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 3/20 0.46
GAA P10253 2/20 0.46
PGR P06401 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 2/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
POLB P06746 1/20 0.44
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
PPARG P37231 3/20 0.42
PPARA Q07869 3/20 0.42
FABP7 O15540 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291368 0.98 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1156687 0.88 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL238320 0.87 PPARG (0.54) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1156729 0.87 GSK3B (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL2291363 0.86 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDTDP1HSD17B10
Bicarbonate SCHEMBL28016109 0.85 PPARG (0.52) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1156688 0.84 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL399266 0.83 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL7017642 0.83 FABP3 (0.44) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL9794488 0.83 MCL1 (0.43) ALDH1A1KDM4EHPGDGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
CN-106536630-B Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties 科思创德国股份有限公司 2019-07-19 CN disclosed
CN-109153776-A Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2019-01-04 CN disclosed
CN-106661318-A Copolycarbonate compositions with branch structures and linear oligomers and improved rheological properties 科思创德国股份有限公司 2017-05-10 CN disclosed
CN-106574109-A Copolycarbonate compositions with cyclic and linear oligomers and improved rheological properties 科思创德国股份有限公司 2017-04-19 CN disclosed
CN-106536629-A Copolycarbonate compositions with branch structures and cyclic oligomers and improved rheological properties 科思创德国股份有限公司 2017-03-22 CN disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed
EP-0434998-B1 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof G E PLASTICS JAPAN LTD (JP) 1996-02-07 EP disclosed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US disclosed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
EP-0488182-A2 Process for producing a polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed