SCHEMBL1156687

SCHEMBL1156687

O=C(Oc1ccccc1-c1ccccc1-c1cccc2ccccc12)Oc1ccccc1-c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
GAA P10253 2/20 0.47
PGR P06401 1/20 0.47
PTGS1 P23219 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
POLB P06746 1/20 0.45
KDM4E B2RXH2 3/20 0.45
HPGD P15428 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
BCHE P06276 1/20 0.43
SLC6A3 Q01959 1/20 0.43
ALOX5 P09917 1/20 0.43
GSK3B P49841 1/20 0.43
ADK P55263 1/20 0.43
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291363 0.98 ALDH1A1 (0.49) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL246023 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL30462997 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL1156690 0.88 ALDH1A1 (0.47) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL238319 0.86 HDAC8 (0.54) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL1156728 0.86 GSK3B (0.48) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL2291368 0.86 ALDH1A1 (0.49) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL5706127 0.85 SLC6A3 (0.52) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL10806722 0.84 GSK3B (0.56) ALDH1A1HSD17B10GAAPGRPTGS1
SCHEMBL37865 0.83 ALDH1A1 (0.65) ALDH1A1HSD17B10GAAPGRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-8044122-B2 Polycarbonate composition containing UV absorber BAYER MATERIALSCIENCE AG (DE) 2011-10-25 US disclosed
US-7879967-B2 End groups containing alkylsiloxane substituted phenol compounds ; extrusion; molding materials BAYER MATERIALSCIENCE AG (DE) 2011-02-01 US disclosed
US-20090258978-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2009-10-15 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-20080249234-A1 Modified Polycarbonates, Polyester Carbonates and Polyesters Having Improved Elongation Behaviour and Flame Resistance BAYER MATERIALSCIENCE AG (DE) 2008-10-09 US disclosed
US-7425358-B2 Copolycarbonates having improved flowability BAYER MATERIALSCIENCE AG (DE) 2008-09-16 US disclosed
US-7345133-B2 Branched polycarbonates BAYER MATERIALSCIENCE AG (DE) 2008-03-18 US disclosed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed
EP-0434998-B1 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof G E PLASTICS JAPAN LTD (JP) 1996-02-07 EP disclosed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US disclosed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed