Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092065 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL20187556 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL28771419 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL29091897 | 0.80 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL29498029 | 0.77 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL11563760 | 0.76 | TRPA1 (0.50) | IDO1TAAR1LMNAAGXT | |
| SCHEMBL8322312 | 0.76 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL24848154 | 0.75 | IDO1 (0.48) | SLC6A2SLC6A3IDO1LMNAHTR2A | |
| SCHEMBL10331596 | 0.74 | IDO1 (0.46) | IDO1TAAR1CYP2A6PPARGPPARA | |
| SCHEMBL5570367 | 0.74 | TAAR1 (0.54) | SLC6A2TAAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173706-A | REACTING WITH MOLYBDENUM HEXAFLUORIDE | INSTITUTE NATIONAL DE RECHERCHE CHIMIQUE APPLIQUEE (FR) | 1979-11-06 | — | — | US | disclosed |