SCHEMBL11567196

SCHEMBL11567196

C1=Nc2ccccc2C1.CC1(C)C=Nc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.32
HTR2A P28223 1/20 0.32
CYP3A4 P08684 2/20 0.30
MEN1 O00255 1/20 0.30
CYP2D6 P10635 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
BCHE P06276 1/20 0.30
CHRM5 P08912 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
PRCP P42785 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL926937 0.82 HTR5A (0.35)
SCHEMBL29639106 0.82 HTR5A (0.35)
Iodide SCHEMBL29258426 0.80 HTR5A (0.37)
Hydrochloric Acid SCHEMBL30881482 0.80 HTR5A (0.34)
SCHEMBL29861109 0.78
SCHEMBL60763 0.78
Methylamine SCHEMBL27882747 0.77 TRPA1 (0.41) TRPA1
Ammonia Solution, Strong SCHEMBL23326973 0.76 TRPA1 (0.43) TRPA1TSHR
Hydrochloric Acid SCHEMBL7530965 0.76 TRPA1 (0.43) TRPA1CYP3A4MEN1KMT2ATSHR
SCHEMBL29940088 0.76 TRPA1 (0.43) TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US disclosed