Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639106 | 1.00 | HTR5A (0.35) | HTR5ACASP3RAB9AATMNPSR1 | |
| Iodide SCHEMBL29258426 | 0.98 | HTR5A (0.37) | HTR5ACASP3RAB9AATMNPSR1 | |
| Hydrochloric Acid SCHEMBL30881482 | 0.98 | HTR5A (0.34) | HTR5ACASP3RAB9AATMNPSR1 | |
| SCHEMBL11567196 | 0.82 | TRPA1 (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL30881490 | 0.82 | CES1 (0.35) | TDP1L3MBTL1PDK2 | |
| SCHEMBL31672941 | 0.78 | — | — | |
| SCHEMBL5486167 | 0.77 | HTR5A (0.33) | HTR5ACASP3RAB9AATMNPSR1 | |
| SCHEMBL28422949 | 0.77 | HTR5A (0.33) | HTR5A | |
| Oxindole SCHEMBL7836705 | 0.76 | AHR (0.58) | CASP3RAB9ASENP8SENP7SENP6 | |
| SCHEMBL29138318 | 0.76 | HTR5A (0.32) | HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1097 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630742-B1 | CHEMILUMINESCENT PROBES FOR IMAGING/DETECTION OF PROTEASES | UNIV RAMOT (IL) | 2023-08-16 | — | — | EP | claimed |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-03 | — | — | US | claimed |
| EP-4219651-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-02 | — | — | EP | claimed |
| CN-115521324-A | Preparation of near-infrared fluorescent probe for detecting beta-lactamase in drug-resistant bacteria | 山西医科大学 | 2022-12-27 | — | — | CN | claimed |
| CN-110944985-B | Chemiluminescent probe for imaging/detection of proteases | 特拉维夫大学拉玛特有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-108884386-B | Chemiluminescent probe for diagnosis and in vivo imaging | 特拉维夫大学拉玛特有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-02-08 | — | — | US | claimed |
| EP-3408349-B1 | CHEMILUMINESCENT FLUOROPHOR-LINKED ADAMANTYLENE-DIOXETANE PROBES AS DIAGNOSTICS OR IN-VIVO IMAGING SENSORS | UNIV RAMOT (IL) | 2021-03-31 | — | — | EP | claimed |
| CN-110064064-B | Contrast agent and application thereof in photoacoustic imaging of brown fat | 四川大学 | 2020-10-23 | — | — | CN | claimed |
| US-20200277647-A1 | CHEMILUMINESCENT PROBES FOR IMAGING/DETECTION OF PROTEASES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-09-03 | — | — | US | claimed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0368327-A2 | Light-sensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-16 | — | — | EP | claimed |
| EP-0176472-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-01-24 | — | — | EP | claimed |
| US-4891305-A | LASERS | RICOH CO., LTD. (JP) | 1990-01-02 | — | — | US | claimed |
| US-4873184-A | ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| EP-0176473-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | claimed |
| US-4251609-A | Isoquinolinedione photoelectrophoretic materials for imaging processes | EASTMAN KODAK COMPANY (US) | 1981-02-17 | — | — | US | claimed |
| EP-0005652-A2 | Electrophoretic migration imaging process and dispersion | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1979-11-28 | — | — | EP | claimed |
| US-4165985-A | PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS | EASTMAN KODAK COMPANY (US) | 1979-08-28 | — | — | US | claimed |
| US-4145215-A | PHOTOCONDUCTIVE PIGMENTS | EASTMAN KODAK COMPANY (US) | 1979-03-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | DHPS, DOHH, DAZAP1 | HTR5A 3859/4885CASP3 668/4885RAB9A 3395/4885 |
| US-20200277647-A1 | CHEMILUMINESCENT PROBES FOR IMAGING/DETECTION OF PROTEASES | ADAM12, ADAM17, PRCP | HTR5A 3611/4885CASP3 232/4885RAB9A 2766/4885 |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | JAK2, MPO, PEAK1 | HTR5A 4193/4885CASP3 1818/4885RAB9A 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.