Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879501 | 0.86 | HDAC1 (0.72) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL2259695 | 0.84 | MAPT (0.70) | KEAP1HDAC2HDAC8HDAC6TDP1 | |
| SCHEMBL10012805 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL10906659 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL9129063 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL10011031 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL10906647 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL10907431 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL10790046 | 0.82 | MAPT (0.74) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL497371 | 0.82 | KEAP1 (0.73) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114377006-A | Absorption enhancer for cinnamic acid derivatives | 株式会社山田养蜂场本社 | 2022-04-22 | — | — | CN | claimed |
| CN-111965941-A | Positive photosensitive polyimide resin composition and use thereof | 浙江福斯特新材料研究院有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-1393438-B | Taxane derivative and its preparing process and usage | Inst of Medical Materials Chinese Academy of Medical Sciences | 2010-11-03 | — | — | CN | claimed |
| CN-100415770-C | 2-{[N-(2-amino-3-(heteroaryl or aryl) propionyl)-aminoacyl]-amino}- alkylboronic acid derivatives | NOVARTIS AG (CH) | 2008-09-03 | — | — | CN | claimed |
| US-7388003-B2 | Δ15-D-Homosteroids with androgenic action | BAYER SCHERING PHARMA AG (DE) | 2008-06-17 | — | — | US | claimed |
| CN-1997659-A | D-carb-17-chloro-16 -ene steroids | SCHERING AG (DE) | 2007-07-11 | — | — | CN | claimed |
| WO-2006138589-A2 | OPIOID RECEPTOR LIGANDS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2006-12-28 | — | — | WO | claimed |
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | claimed |
| EP-1399468-B1 | 2-((N-(2-AMINO-3-(HETEROARYL OR ARYL)PROPIONYL)-AMINOACYL)-AMINO)-ALKYLBORONIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2006-02-15 | — | — | EP | claimed |
| US-20050234111-A1 | D-homo-17-chlor-16(17)-ene steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-10-20 | — | — | US | claimed |
| US-5763438-A | ANTIVIRAL AGENTS | SEIKAGAKU CORPORATION (JP) | 1998-06-09 | — | — | US | claimed |
| WO-1997019060-A1 | 3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS | ZENECA LIMITED (GB) | 1997-05-29 | — | — | WO | claimed |
| US-5358939-A | For applying to soils, seeds, plants, or for storage of cereal grains | ROHM AND HAAS COMPANY (US) | 1994-10-25 | — | — | US | claimed |
| EP-0576201-A2 | Fungicidal 1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| US-4959362-A | FREE RADICAL SCAVENGERS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1990-09-25 | — | — | US | claimed |
| EP-0124216-B1 | C-20- AND C-23-MODIFIED MACROLIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | claimed |
| EP-0124216-A1 | C-20- and C-23-modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-11-07 | — | — | EP | claimed |
| US-4468511-A | C-20- And C-23-Modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | claimed |
| US-4260551-A | ALIPHATIC OR AROMATIC ESTERS, ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-07 | — | — | US | claimed |
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234111-A1 | D-homo-17-chlor-16(17)-ene steroids | CYP17A1, HSD17B11, HSD17B7 | KEAP1 2164/4885FFAR1 1891/4885ALDH1A1 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.