SCHEMBL497371

SCHEMBL497371

O=C(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.73
FFAR1 O14842 2/20 0.67
ALDH1A1 P00352 2/20 0.67
TDP1 Q9NUW8 3/20 0.62
TRPA1 O75762 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
HDAC2 Q92769 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC1 Q13547 2/20 0.60
HDAC3 O15379 1/20 0.60
MAPK1 P28482 1/20 0.60
ADRA1A P35348 1/20 0.60
HDAC4 P56524 1/20 0.60
SLC6A3 Q01959 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107423 0.97 KEAP1 (0.70) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL712597 0.97 KEAP1 (0.70) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL19561359 0.91 HDAC1 (0.69) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL5355399 0.91 KEAP1 (0.75) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL26624571 0.91 KEAP1 (0.61) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL5598977 0.90 KEAP1 (0.67) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL4077641 0.89 ALDH1A1 (0.61) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL11741034 0.89 KEAP1 (0.59) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL19625551 0.89 MAPT (0.68) KEAP1FFAR1ALDH1A1TDP1TRPA1
SCHEMBL9705008 0.89 KEAP1 (0.59) KEAP1FFAR1ALDH1A1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116371450-B Composite carrier supported bimetallic catalyst and preparation method and application thereof 昆明理工大学 2026-05-19 CN claimed
CN-116925057-A High-thermal stability hole transport material based on dibenzothiophene end group and synthesis method thereof 南京理工大学 2023-10-24 CN claimed
CN-116371450-A Composite carrier supported bimetallic catalyst and preparation method and application thereof 昆明理工大学 2023-07-04 CN claimed
CN-114716439-A Method for synthesizing 6-thiopurine derivative by copper catalysis 陕西师范大学 2022-07-08 CN claimed
EP-3527576-B1 PROPYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION EVONIK OPERATIONS GMBH (DE) 2020-11-18 EP claimed
CN-111328280-A Methods of making and using endoxifen 阿托萨治疗学公司 2020-06-23 CN claimed
WO-2014153099-A2 METHOD FOR USING EXHALED BREATH TO DETERMINE THE PRESENCE OF DRUG Pulmonary Analytics (US) 2014-09-25 WO claimed
US-20140288454-A1 Method For Using Exhaled Breath to Determine the Presence of Drug Pulmonary Analytics (US) 2014-09-25 US claimed
CN-102417553-B Hydroxyalkyl aryl ketone photoinitiator capable of reducing volatile organic compound (VOC) discharge until elimination of VOC discharge NEWSUN POLY TECH CO LTD 2013-04-10 CN claimed
CN-102417553-A Hydroxyalkyl aryl ketone photoinitiator capable of reducing volatile organic compound (VOC) discharge until elimination of VOC discharge NEWSUN POLY TECH CO LTD 2012-04-18 CN claimed
US-20050026081-A1 Volume hologram recording photosensitive composition, and volume hologram recording medium using the same FUJI PHOTO FILM CO., LTD. 2005-02-03 US claimed
CN-1043575-C Silylated acetylcholinesterase inhibitors MERRELL DOW PHARMA (US) 1999-06-09 CN claimed
EP-0772609-B1 CYCLIC KETONE PEROXIDE FORMULATIONS AKZO NOBEL NV (NL) 1999-02-24 EP claimed
EP-0498301-B1 Process for preparing a watersoluble (form)aldehyde resin and adhesive composition containing the same FULLER H B LICENSING FINANC (US) 1998-10-21 EP claimed
US-5808110-A TRANSPORTABLE; STORAGE STABLE AKZO NOBEL NV (NL) 1998-09-15 US claimed
EP-0772609-A1 CYCLIC KETONE PEROXIDE FORMULATIONS Akzo Nobel N.V. (NL) 1997-05-14 EP claimed
WO-1996003397-A1 CYCLIC KETONE PEROXIDE FORMULATIONS AKZO NOBEL N.V. (NL) 1996-02-08 WO claimed
EP-0341720-B1 Light-sensitive compositions FUJI PHOTO FILM CO LTD (JP) 1995-02-08 EP claimed
EP-0341720-A2 Light-sensitive compositions Fuji Photo Film Co., Ltd. (JP) 1989-11-15 EP claimed
US-4824982-A Method for the cleavage of organic siloxanes, and products and applications thereof HUELS TROISDORF AG (DE) 1989-04-25 US claimed