SCHEMBL11567657

SCHEMBL11567657

C=CCn1cnc2cc(C(=O)OCC)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.53
RAB9A P51151 3/20 0.53
HPGD P15428 3/20 0.47
ATM Q13315 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
F10 P00742 2/20 0.45
RECQL P46063 1/20 0.45
MAPK10 P53779 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 1/20 0.44
NLRP3 Q96P20 1/20 0.44
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
F2 P00734 1/20 0.43
PRSS1 P07477 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9678422 0.88 FGFR1 (0.55) NPC1RAB9AHPGDSMN1; SMN2ALDH1A1
SCHEMBL9126131 0.86 RAB9A (0.57) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL9680193 0.84 FGFR1 (0.53) NPC1RAB9AHPGDKMT2AF10
SCHEMBL14800208 0.84 HPGD (0.53) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL3616090 0.82 FGFR1 (0.52) HPGDF10ALDH1A1GAALMNA
SCHEMBL14800316 0.81 MEN1 (0.54) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL9038215 0.81 HPGD (0.53) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL6806002 0.80 HDAC1 (0.52) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL10354608 0.79 KMT2A (0.59) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL9461934 0.79 HPGD (0.51) NPC1RAB9AHPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152163-A Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US disclosed