SCHEMBL9680193

SCHEMBL9680193

C=CCn1cnc2cc(C(C)=O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.53
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
SMN1; SMN2 Q16637 5/20 0.45
HTT P42858 1/20 0.45
HPGD P15428 1/20 0.44
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
HCAR3 P49019 1/20 0.43
TBXA2R P21731 1/20 0.42
F10 P00742 2/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TP53 P04637 3/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3616090 0.89 FGFR1 (0.52) FGFR1HPGDALDH1A1HCAR3TBXA2R
SCHEMBL9678422 0.87 FGFR1 (0.55) FGFR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL1539115 0.85 MAPT (0.63) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL11567657 0.84 NPC1 (0.53) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL11008842 0.84 F10 (0.46) FGFR1RAB9ASMN1; SMN2HTTHPGD
SCHEMBL6112712 0.84 NPC1 (0.62) FGFR1NPC1RAB9ASMN1; SMN2HTT
SCHEMBL6112850 0.81 HPGD (0.57) FGFR1NPC1RAB9ASMN1; SMN2HTT
SCHEMBL19848314 0.79 ALDH1A1 (0.47) FGFR1NPC1RAB9ASMN1; SMN2HTT
SCHEMBL6281552 0.79 FGFR1 (0.52) FGFR1NPC1RAB9ASMN1; SMN2HTT
SCHEMBL9680188 0.76 ALDH1A1 (0.45) HPGDALDH1A1MAPTHDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166046-A Light sensitive element with sensitizers KONICA CORPORATION (JP) 1992-11-24 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
US-4152163-A Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US disclosed
US-4147553-A CYANINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed