Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891578 | 0.80 | SLC6A2 (0.48) | ESR1ESR2KDM4EALDH1A1TAAR1 | |
| SCHEMBL11566623 | 0.80 | IDO1 (0.38) | ESR1ESR2DPP4KDM4EALDH1A1 | |
| SCHEMBL3160096 | 0.80 | ESR1 (0.42) | ESR1ESR2DPP4CASRKDM4E | |
| SCHEMBL14376105 | 0.77 | LOXL2 (0.40) | ESR1ESR2DPP4IDO1LOXL2 | |
| SCHEMBL14446924 | 0.76 | KDM4E (0.39) | ESR1ESR2DPP4CASRKDM4E | |
| SCHEMBL13271144 | 0.74 | TAAR1 (0.40) | ESR1ESR2DPP4CASRKDM4E | |
| SCHEMBL22728291 | 0.73 | LMNA (0.37) | ESR1ESR2DPP4KDM4EIDO1 | |
| SCHEMBL4661340 | 0.73 | IDO1 (0.42) | ESR1KDM4EIDO1LOXL2MAOB | |
| SCHEMBL2615503 | 0.72 | ESR1 (0.58) | ESR1KDM4EIDO1LOXL2TAAR1 | |
| SCHEMBL28444880 | 0.72 | IDO1 (0.46) | IDO1LOXL2MAOBTAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |