Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 6/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567948 | 0.80 | CTSK (0.38) | MMP1CTSBCTSKCTSLCTSS | |
| SCHEMBL7269855 | 0.77 | SLC7A5 (0.41) | CTSBCTSKCTSLCTSSPSEN1 | |
| SCHEMBL11568486 | 0.76 | MME (0.41) | CTSKPSMB5 | |
| SCHEMBL11568489 | 0.75 | CTSD (0.45) | CTSBCTSKBACE1PSEN1PSEN2 | |
| SCHEMBL11568405 | 0.73 | MME (0.50) | MMP1CTSBCTSKCTSD | |
| SCHEMBL11568394 | 0.73 | MME (0.50) | MMP1CTSBCTSKCTSD | |
| SCHEMBL11567621 | 0.71 | CTSK (0.55) | CTSBCTSKCTSLCTSSCTSD | |
| SCHEMBL11567622 | 0.71 | CTSK (0.55) | CTSBCTSKCTSLCTSSCTSD | |
| SCHEMBL11568492 | 0.71 | BACE1 (0.36) | BACE1PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL11568557 | 0.71 | CTSK (0.54) | CTSBCTSKCTSLCTSSCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |