Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27847496 | 0.80 | KMT2A (0.46) | TDP1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3299147 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HSD17B10GSR | |
| SCHEMBL286963 | 0.77 | GSR (0.43) | TDP1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL22323630 | 0.77 | GSR (0.43) | ALDH1A1KMT2AMEN1LMNAGSR | |
| SCHEMBL27388028 | 0.77 | GSR (0.36) | HTTTDP1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5932816 | 0.76 | GSR (0.42) | TDP1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL2208139 | 0.76 | HPGD (0.40) | ALDH1A1KMT2AMEN1MAPTGSR | |
| Hydrochloric Acid SCHEMBL27718932 | 0.75 | ACP1 (0.37) | TDP1ALDH1A1KMT2APOLBMEN1 | |
| Methyl Alcohol SCHEMBL9278113 | 0.75 | NPSR1 (0.41) | HTTTDP1ALDH1A1KMT2AMAPT | |
| SCHEMBL258789 | 0.74 | GSR (0.41) | ALDH1A1KMT2ALMNAGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002564-A1 | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1979-06-27 | — | — | EP | disclosed |