SCHEMBL286963

SCHEMBL286963

O=C(O)OC(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.43
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39
LMNA P02545 3/20 0.38
MAPK1 P28482 2/20 0.38
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22323630 0.89 GSR (0.43) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL5932816 0.87 GSR (0.42) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL4441195 0.86 GSR (0.39) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL258789 0.85 GSR (0.41) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL3299147 0.85 ALDH1A1 (0.49) GSRCYP2D6SRCKMT2AALDH1A1
SCHEMBL38107 0.85 NPSR1 (0.43) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL5932183 0.85 GSR (0.41) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL10640253 0.85 GSR (0.41) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL4277062 0.84 TSHR (0.50) GSRLMNAMAPK1KMT2ACES2
SCHEMBL27847496 0.84 KMT2A (0.46) GSRKMT2AALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 667 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350283-A Prazomycin impurity H and preparation method thereof 上海上药新亚药业有限公司 2025-01-24 CN claimed
CN-105555759-A Compounds with antibacterial activity FUND MEDINA CT DE EXCELENCIA EN INVESTIG DE MEDICAMENTOS INNOVADORES EN ANDALUCIA 2016-05-04 CN claimed
WO-2005058246-A2 METHOD FOR PREPARING RADIOLABELED THYMIDINE MOLECULAR TECHNOLOGIES, INC. (US) 2005-06-30 WO claimed
WO-2026089784-A2 COMPOUNDS AND COMPOSITIONS FOR CONJUGATION TO BIOLIGANDS FOR IMAGING AND RADIOPHARMACEUTICAL APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2026-04-30 WO disclosed
EP-4667537-A1 PRIMER COMPOSITION, LAMINATE, AND METHOD FOR PRODUCING LAMINATE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-12-24 EP disclosed
US-20250382500-A1 PRIMER COMPOSITION, LAMINATE, AND METHOD FOR PRODUCING LAMINATE TOKYO OHKA KOGYO CO LTD (JP) 2025-12-18 US disclosed
US-20250271751-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, LOWER LAYER FILM, METHOD FOR PRODUCING STRUCTURE HAVING PHASE-SEPARATED STRUCTURE, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2025-08-28 US disclosed
US-20250189895-A1 METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-06-12 US disclosed
CN-120065622-A Photosensitive resin composition and method for producing microlens 东京应化工业株式会社 2025-05-30 CN disclosed
US-20250172872-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE COMPOSITION, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, AND METHOD OF MANUFACTURING PLATED ARTICLE TOKYO OHKA KOGYO CO., LTD. (JP) 2025-05-29 US disclosed
US-12281126-B2 Inhibitors of cyclin-dependent kinase 7 and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-04-22 US disclosed
WO-2001096336-A2 6,5-FUSED BICYCLIC HETEROCYCLES WARNER-LAMBERT COMPANY (US) 2001-12-20 WO disclosed
WO-2000056925-A2 METHODS FOR SINGLE NUCLEOTIDE POLYMORPHISM DETECTION ACLARA BIOSCIENCES, INC. (US) 2000-09-28 WO disclosed
US-5908926-A 5'to 3' nucleic acid synthesis using 3'-photoremovable protecting group DUKE UNIVERSITY (US) 1999-06-01 US disclosed
EP-0815114-A4 NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS UNIV DUKE (US) 1999-02-24 EP disclosed
US-5721099-A Complex combinatorial chemical libraries encoded with tags TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-02-24 US disclosed
EP-0815114-A1 NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS DUKE UNIVERSITY (US) 1998-01-07 EP disclosed
WO-1997026873-A1 ANTIMICROBIAL AURONE DERIVATIVES PHYTERA, INC. (US) 1997-07-31 WO disclosed
WO-1996028457-A1 NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS DUKE UNIVERSITY (US) 1996-09-19 WO disclosed
EP-0114341-B1 DYE-CONTAINING LAYER IN A PHOTOPOLYMERISABLE COMPOSITION, AND PROCESS FOR OBTAINING RELIEF AND PRINTING FORMES BASF Aktiengesellschaft (DE) 1991-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12281126-B2 Inhibitors of cyclin-dependent kinase 7 and uses thereof CDK9, CDK7, CDK1 GSR 3140/4885CYP2D6 1280/4885SRC 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.